The feasibility for ALP detection based on inner filter effect. (A
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Download scientific diagram | The feasibility for ALP detection based on inner filter effect. (A) The fluorescence spectra of ZnSe@ZnS QDs and Mn:ZnS QDs in the presence of different substances. (a) None, (b) PNPP (600 μM), (c) PNPP (600 μM) and ALP (100 U per L). (B) The absorption spectrum of PNPP (a) and the excitation spectra of ZnSe@ZnS QDs (b), Mn:ZnS QDs (c). (C) The absorption spectra of incubation mixture in the presence of various activites of ALP (from bottom to top, 0, 16, 32, 64, 96 U per L). (D) The absorption spectra of PNPP (a), PNP (c) and the emission spectra of ZnSe@ZnS QDs (b), Mn:ZnS QDs (d) from publication: A novel and sensitive ratiometric fluorescent quantum dot-based biosensor for alkaline phosphatase detection in biological samples via the inner-filter effect | Alkaline phosphatase (ALP) is an important biomarker whose abnormal level in activity is associated with hepatobiliary, skeletal, and renal diseases as well as cancer. Herein, we synthesized ZnSe@ZnS quantum dots (ZnSe@ZnS QDs) and Mn-doped ZnS quantum dots (Mn:ZnS QDs) as | ALP, Alkaline Phosphatase and Fluorescence | ResearchGate, the professional network for scientists.
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